The Belmont principle of beneficence requires that potential benefits must justify what?

The Belmont principle of beneficence emphasizes the ethical obligation to maximize potential benefits while minimizing possible harms to participants involved in research. This principle mandates that researchers carefully evaluate the risks of harm that may arise from their studies.

In this context, the correct answer highlights that any potential benefits derived from the research should not only be substantial but must also be weighed against the risks of harm to participants. The goal is to ensure that any adverse effects or risks are justified by the benefits of the research findings, thereby safeguarding the well-being and rights of participants.

While financial costs, time commitments, and institutional review board approvals are important considerations in research ethics, they do not directly relate to the principle of beneficence in the same way as the balance between risk and benefit. Thus, the focus on justifying the risks of harm against potential benefits aligns with the ethical requirements set forth by the Belmont Report, highlighting the importance of ensuring participant protection while advancing knowledge through research.